las

Welcome all seeking refuge from low carb dogma!

“To kill an error is as good a service as, and sometimes even better than, the establishing of a new truth or fact”
~ Charles Darwin (it's evolutionary baybeee!)

Thursday, November 23, 2017

Happy Thanksgiving!


I have much to be thankful for this year, and this is a day for celebration.    Wishing you all the best day, I'm thankful for all who read here!  




I'll be making an apple pie (crust from scratch too!) and there's a slice with my name on it ... it will be worth every calorie!  Also my sister makes the BEST pecan pie only once a year on Thanksgiving, so you better believe I'm having a slice of that too!  I hope you all enjoy the special foods at your celebrations, but more importantly the family and friends you celebrate with.   Have a great day!


Thursday, November 9, 2017

Diabetes Un-Funged



The Noakes Foundation has put out a new book entitled Diabetes Unpacked* , edited by Dr. Zoe Harcombe PhD.   It is a compilation of chapters written by a who's who of the low carborati.  This installment deals with Chapter 3 by Dr. Jason Fung, a nephrologist masquerading as an obesity specialist and diabetologist.  He has no formal training in either, and his grasp of some pretty basic physiology is tenuous at best.  That latter "charge" can be backed up by fact checking (or attempting to fact check that which isn't simply Fung POOP (Pulled Out Of Posterior)) any of his various blog articles, books, podcasts or YouTube videos.  

* That's my Amazon affiliate link


This post will be an evolving one of sorts that I'll bump if and when content is added.  I've avoided giving Fung much "ink" here, frankly because I never thought anyone would take him seriously enough to deserve it.  Clearly I was wrong.  There's apparently no limit as to who can become the latest #LCHF-lavor.  Jimmy Moore still has a following.  #IRestMyCase 😎

Dr. Jason Fung on Insulin Resistance and Its Causes
from:  Insulin Toxicity and How to Cure Type 2 Diabetes

Monday, October 30, 2017

FREE!!!! Carb Sanity Academy presents: Healthy for the Holidays


This mix of snarkasm and practical advice is brought to you by Facebook Memories reminding me of a post I made around a year ago -- The #LCHF Weight Loss Industry & Evangelizing Low Carb -- and the upcoming Keto Clarity Academy event featuring Melanie Miller and Jimmy Moore "influencing" people on how to stay healthy for the holidays.

The holiday season will be soon upon us, and even those who celebrate no December holidays will likely still have to navigate related social engagements. 

Let me preface this by saying that I recognize there are a number of people who absolutely cannot, or probably should not, stray from their dietary regimen.  There are others who, when they do, have a much harder time getting "back on the wagon" compared to whatever issues staying on plan will cause.  If you are any of these people, this blog post is not for you.  This blog post is aimed at all of those who are angst-ridden going into and through the upcoming holidays and associated social occasions.  Perhaps you're currently engaged in losing weight, or you've lost weight and are working to maintain it.  This post is for you. 

Since 2007 I have been doing some form of this strategy when either losing or maintaining.  If you look around the various dietary communities, you'll see a common theme.  Of course there are always exceptions, but those who struggle with falling short of goals and/or maintaining their losses while remaining (largely) true to their dietary framework, almost invariably fall into the food substitute trap.  The problem with many of these foods is that they:

  • Remove any "magic" that eliminating certain foods or food groups has on reducing ad libitum caloric intake.
  • Can cause increased intake of foods with a "health halo" (e.g. it's fill-in-the-blank so it's "healthy" ... heck, I can even eat that for breakfast!)
  • Are rarely as good as the "real thing", ultimately leaving you with some degree of dissatisfaction and deprivation.   
  • Often contain more calories than the foods they are replacing

All of the above hold for various dietary paradigms.  The last bullet point is especially true for those following various low carb ones. 

With all of this in mind, first up, my FREE Carb Sanity Academy tips for getting through the rest of 2017 without messing with your goals.   (And then the snarkasm 😎)

Sunday, October 22, 2017

β-Cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-β-cell relationships

BUMP NOTICE: 

I'm bumping this post due to some recent discussions on social media regarding the reversibility of Type 2 Diabetes and the role of low carbohydrate diets in the growing "curing diabetes" paradigm.  Recently Dr. Roy Taylor (the investigator I most closely associate with the crash diet, though this is an extensive group) and colleagues, who implemented a "crash diet" to cure diabetes -- by reducing pancreatic and hepatic (liver) fat concurrently with rapid weight loss -- published the following in BMJ:  Beating type 2 diabetes into remission.    The criteria are non-diabetic markers for a period following reversal of the progression.  Here is where various low carbohydrate interventions "fail", as many are able to maintain normoglycemia only by avoiding carbohydrates.  The question remains if this is effectively the same as other reversals.  I contend it is not, as normal pancreatic function -- specifically GSIS -- has not been restored.  Anecdotally (because we really don't have truly long term studies on LCHF following weight loss phase), many LCHFers see rising fasting levels, and one outspoken advocate, Tim Noakes, is among the many who remain on metformin to manage glucose levels.  The burning question, that remains unstudied by the advocates of low carbohydrate diets, is whether such diets will slow, halt or reverse the disease itself.  Here is where rodent data is NOT promising, especially when diabetes is viewed across the full metabolic milieu rather than the isolated metric of blood glucose. 




ORIGINAL PUBLISH DATE:  July 21, 2011


β-Cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-β-cell relationships

Yes, this is a rat study, but it seems applicable in light of the recent Diabetes "Crash Diet" Cure and the reductions in pancreatic fat seen in the study.  The study and the pancreatic fat issue were discussed here.  Summary:  11 diabetics followed a 600 cal/day diet for 8 weeks and regained normal insulin secretion and glycemic control.  The restored glucose induced insulin secretion (GSIS) was attributed to reduction in pancreatic fat content.

The investigators in the current study had this to say in the introduction (bolded emphasis is mine):

Saturday, September 30, 2017

The Insulin Paradox

I think this post has needed a bump for a while.     I also think the data on growing animals eating a keto diet should be cause for at least caution in encouraging such diets for kids, teens or even young adults.

ORIGINAL POST DATE 3/20/2012

One of the more difficult things to sort out from the enormous amount of information out there is the actual effect, if any, of dietary composition on resulting body composition.  This is complicated from the get-go by many rodent studies that are done on reproductively mature animals that are still growing.  How to compare this to humans who cease growing vertically once they reach adulthood?  Next we have to sort through the studies that are done, and the implications of them, in the context of weight loss/underfeeding vs. those in the context of weight gain/overfeeding.  Clearly there are compensatory mechanisms at play in both situations that are drastically different.  Lastly, and here's where we probably have the least amount of information, and practically nothing in humans, what role does one's dietary composition have on their body composition over the long haul for a "normal" weight stable adult?    Verifiable science basically fails us on this last point, and we're left mostly to the "wolves" of the diet/fitness industry -- e.g. body builders,  trainers and nutritionists for elite athletes, etc. -- for their anecdotal reports.  I don't mean to disparage these folks with the term wolves (hence the quotes), but we can never separate the reports from the reality when there's money on the line in a world where ads are required to include "results not typical" disclaimers.  While I'm not saying all of these folks, or even a majority, are of the 2am infomercial variety, the claims remain largely unverifiable.  It would sure be cool if there was a privacy-sparing way to collect verifiable body composition, dietary and activity data for a large population of free-living humans, eh?

Monday, September 18, 2017

Bump: The Diabetes "Crash" Cure & Pancreatic Fat

Bumping Again!


New Article in BMJ:  Analysis: Beating type 2 diabetes into remission*

The original posting of this was shortly after the first papers published on the success of a very low calorie diet -- essentially a 6-800 calorie protein-sparing-modified-fast, protein shakes + non-starchy veggies -- in curing diabetes in relatively short order.  You may also be interested in the following posts:

The Diabetes "Crash" Cure Revisited (a follow-up to this one)
Diabetes "Crash" Cures: VLCal vs. VLCarb

Check Featured Comment (if any) for further updates from me.

*In light of commentary below, I'll add that I am not a fan of using the term remission here.  Cancer does seem to strike at random most times and recurrence seems to be equally random.  At best we have few if any ways to predict who will see cancer return etc.  But Type 2 diabetes doesn't work that way in most.  The source of the beta cell dysfunction is pretty well known now, and that it IS reversible and can be restored is as well.  An underlying genetic propensity towards T2 (e.g. weight distribution and having a low personal adipose storage threshold) is not the same as having an active disease or condition.  There's considerable evidence that those whose diabetes resolved following gastric bypass do not see it return -- in other words they haven't worn out their pancreases and just kick the can of beta-cell exhaustion (a model that has been invalidated quite thoroughly at this point) down the road.

In my opinion, diagnosis of T2 needs to be followed by a much more aggressive lifestyle change "prescription" than is currently given.  Sadly, the medical establishment would rather add obesity to its lists of chronic, incurable lifelong diseases than adjust their model for existing disease that turns out to be curable after all.


Wednesday, September 13, 2017

Keto Clarity Academy ~ Medical Disclaimer


Blogstress Note:  I'm trying to finish up a project outside the Asylum, have had lots of computer issues that have made this frustrating to say the least, coupled with family obligations and "real job" starting back up.  An unfinished, older, now past-its-shelf-date post went live the other day that I have since unpublished.  I may or may not re-publish it merged with another at some point.

I've been meaning to weigh in on the whole Keto Clarity Academy launched by Jimmy Moore and Melanie Miller (of Evangelizing Low Carb fame), and a more in depth look will have to wait until higher priorities are fulfilled.  



Here is the current front page of Keto Clarity Academy.  Finally, the stock photos have been replaced, though at this time we still don't have bios and official roles of the four ladies joining Jimmy and Melanie in this endeavor.


For $75 (down from $100) you can take KETO 101 based on Jimmy's book.  The blurb on the bottom reads:

KETO Clarity Academy
Based on the best selling book by Author & pod-caster Jimmy Moore. The KETO Clarity Academy is a fantastic starting point for the ketogenic lifestyle. KCA specializes in helping clients achieve their personal goals, improve health gains and receive knowledge of the science of the ketogenic lifestyle.

Thursday, August 31, 2017

PURE Rubbish


Let me preface this post by saying I'm a bit time constrained, and computer issues have made my life miserable these past few days.   However a new article from the PURE study was recently published in Lancet, and I wish to add some limited commentary to the mix.  

First things first, the links:
Secondly, I've tweeted these links out.  Commentary by others:
And now for my favorite headline!

Thursday, August 17, 2017

That Seven Countries White Paper and Ancel Keys' Six Country Plot


Summary:

  • A white paper has been published by the True Health Initiative attempting to set some things straight vis a vis Ancel Keys and his Seven Countries Study
  • Such discussions will always involve the erroneous conflation of that 1970s study and Keys' 1953 "Six Countries Plot"
  • ANCEL KEYS DID NOT CHERRY PICK.   In 1953, it was "possible to get fully comparable dietary and vital statistics data from 6 countries" from 1948-9.  
  • Yerushalmy originally put forth data from 12 and then 22 countries.   These data were from different sources and for different classifications of disease vs. that used by Keys.
  • NEITHER set of data used by Y&H even existed in 1953, so it could not have even been available to Keys.
  • Zoe Harcombe is a terrible researcher at best.  Some institutions will give a PhD to pretty much anyone these days.



Wednesday, August 16, 2017

Tom Naughton Doubles Down on Kooky Kalorie Klaims for Fat Head Kids


Preface:


I have to say this.  Sorry, not sorry.  If you have children, and you want to help them with nutrition and health as they grow, teach them about food and teach them how to cook.   Get your own weight and health under control (if it's a problem) so that you can pass down good habits to your children.  Or do nothing.  None of my business.  But whatever you do, do not buy your child a copy of Fat Head Kids or let them within 50 yards of a showing of the Fat Head Kids movie if it ever comes out.  Put a block on your Hulu or whatever streaming service it is eventually on.  I cannot recommend more strongly against this.

Every time I have watched snippets of some video of Tom talking about this book, or read the preview content on Amazon, I just get utterly creeped out by the whole thing, and Tom Naughton specifically.  Books for children should not include shirtless pictures of the middle aged author who goes on about boy boobs.  

Tom seems to be working through his unresolved childhood issues and perhaps even ongoing body image issues, and has a weird obsession with "moobs".  How else to explain a chapter entitled "Bad Food Makes Boy Boobs"??   Never mind that this topic is irrelevant to half of his prospective audience and his own two children.